Sulkava R, Amberla K
Acta Neurol Scand. 1982 Jun;65(6):651-60. doi: 10.1111/j.1600-0404.1982.tb03118.x.
Neuropsychological performance was investigated in 36 presenile patients with Alzheimer's disease and 35 patients with senile dementia of Alzheimer type by using Luria's test methods. The most deteriorated performances in both groups were in memory, intellectual, higher visual and motor functions, and in orientation. The neuropsychological functions deteriorated gradually in the course of the disease process so that the shape of the performance profile was preserved. The progression of the disease seemed to be more rapid in senile patients but neuropsychologically there were no significant differences between Alzheimer's disease and senile dementia of Alzheimer type. They seemed to form a continuum of one disease. Luria's neuropsychological investigation turned out to be a useful method in the assessment of at least moderate to severe dementia.
采用鲁利亚测试方法，对36例早老性阿尔茨海默病患者和35例阿尔茨海默型老年性痴呆患者的神经心理表现进行了研究。两组患者中，记忆、智力、高级视觉和运动功能以及定向功能受损最为严重。在疾病进程中，神经心理功能逐渐恶化，因此表现特征的形状得以保留。老年性患者的疾病进展似乎更快，但在神经心理学方面，阿尔茨海默病与阿尔茨海默型老年性痴呆之间没有显著差异。它们似乎构成了一种疾病的连续体。鲁利亚神经心理学调查结果表明，该方法在评估至少中度至重度痴呆方面是一种有用的方法。
