Roudier M, Marcie P, Podrabinek N, Lamour Y, Davous P
Hôpital Charles Richet, Villiers-le-Bel.
Encephale. 1989 Jul-Aug;15(4):397-403.
Forty six patients affected by senile dementia of the Alzheimer type and 20 control subjects of similar age, sex and educational level have been studied, using a quantified neuropsychological battery (Wechsler memory scale, Raven progressive matrices and quantified tests for aphasia, apraxia and agnosia). There was a significant correlation between the scores of all cognitive functions with one another and with the Mini Mental State. The results show a rather global impairment of cognitive functions in these patients and suggest that intellectual impairment progresses as a continuum in senile dementia of the Alzheimer type.
对46名患有阿尔茨海默型老年痴呆症的患者以及20名年龄、性别和教育水平相近的对照受试者进行了研究,采用了一套量化的神经心理测试组合(韦氏记忆量表、瑞文渐进性矩阵以及失语症、失用症和失认症的量化测试)。所有认知功能的得分之间以及与简易精神状态检查得分之间均存在显著相关性。结果显示这些患者的认知功能存在相当全面的损害,表明在阿尔茨海默型老年痴呆症中,智力损害呈连续进展。