Woo R, Garrow J S, Pi-Sunyer F X
Am J Clin Nutr. 1982 Sep;36(3):470-7. doi: 10.1093/ajcn/36.3.470.
The effect of increased physical activity on energy intake and balance was investigated in six obese women (mean 167% above ideal body weight) voluntarily hospitalized for metabolic balance studies. Three 19-day treatments-one sedentary and two with treadmill exercise which increased daily expenditure to 110% (mild) and 125% (moderate) of sedentary expenditure-were imposed on each subject. Individual daily expenditure and ad libitum intake were determined by activity diaries and covert monitoring, respectively. Subjects selected and did not not change an intake level which allowed for energy balance during the sedentary period only. Therefore, the difference between intake and expenditure between treatments was significantly different (sedentary 11, mild -114, and moderate -369 kcal/day). The negative balance observed with mild and moderate exercise was obtained because while expenditure was raised with exercise, no compensatory increase in intake occurred. Moderate, realistic levels of activity did not regulate intake.
对六名肥胖女性（平均比理想体重高167%）进行了代谢平衡研究，她们自愿住院，以调查增加身体活动对能量摄入和平衡的影响。对每位受试者进行了三种为期19天的治疗——一种是久坐不动，另外两种是在跑步机上锻炼，使每日能量消耗分别增加到久坐时能量消耗的110%（轻度）和125%（中度）。个体每日能量消耗和随意摄入量分别通过活动日记和隐蔽监测来确定。受试者选择并维持了仅在久坐期间能实现能量平衡的摄入水平，没有改变。因此，不同治疗方式下的摄入量和消耗量之间存在显著差异（久坐时为11千卡/天，轻度锻炼时为 -114千卡/天，中度锻炼时为 -369千卡/天）。观察到轻度和中度运动时出现负平衡，是因为虽然运动使能量消耗增加，但摄入量没有相应的补偿性增加。适度、现实水平的身体活动并不能调节摄入量。
