Stainer G A, Shaw E L, Binder P S, Zavala E Y, Akers P
Arch Ophthalmol. 1982 Sep;100(9):1473-7. doi: 10.1001/archopht.1982.01030040451017.
A patient underwent a radial keratotomy (RK) to reduce residual astigmatism that occurred after a corneal transplant. The patient enjoyed immediate good vision, but later intense glare, photophobia, and pain forced him to quit work. Five months later the graft became cloudy, and superficial vascularization developed in the radial scars. An 8.5-mm penetrating keratoplasty was performed 5 1/2 months after RK. Analysis of the corneal button revealed diffuse epithelial edema, epithelial ingrowth into the incisions, an irregularly thickened epithelial basement membrane, immature hemidesmosomes, focal malapposition of Bowman's layer, marked cellularity of the stroma around the margins of the incisions, and posterior folds in Descemet's membrane. Our analysis of this specimen suggests RK may carry a risk of optical and visual aberrations by producing multiple defects in the anterior and posterior aspects of the cornea.
一名患者接受了放射状角膜切开术（RK），以减少角膜移植后出现的残余散光。患者术后立即获得了良好的视力，但后来强烈的眩光、畏光和疼痛迫使他停止工作。五个月后，移植片变得混浊，放射状瘢痕处出现了浅层血管化。在RK术后5个半月进行了8.5毫米穿透性角膜移植术。对角膜植片的分析显示有弥漫性上皮水肿、上皮长入切口、上皮基底膜不规则增厚、半桥粒不成熟、Bowman层局部错位、切口边缘周围基质明显细胞增多以及Descemet膜后褶。我们对该标本的分析表明，RK可能通过在角膜前后表面产生多个缺陷而带来光学和视觉像差的风险。
