Binder P S, Stainer G A, Zavala E Y, Deg J K, Akers P H
Arch Ophthalmol. 1983 Jul;101(7):1113-6. doi: 10.1001/archopht.1983.01040020115020.
We performed eight partially penetrating incisions in 19 eye-bank, 12 nonhuman primate, and 34 canine eyes. Evaluation of the posterior corneal surface by vital staining, correlative microscopy, with corneal incisions set from 80% to 110% of central pachymetric thickness, in three eyes demonstrated damage to the endothelium without anterior chamber perforation. Posterior folds in Descemet's membrane under an incision site was present in all specimens. Potential optical aberrations could be produced about the visual axis depending on the direction of the corneal incisions. Based on this study, the radial keratotomy procedure performed with up to eight deep incisions may produce optic defects. We recommend animal studies to assess the long-term effects of this procedure on the cornea and especially the endothelium.
我们在19只眼库眼、12只非人灵长类动物眼和34只犬眼中进行了8个部分穿透性切口。通过活体染色、相关显微镜检查对后角膜表面进行评估，角膜切口设置为中央角膜厚度的80%至110%，三只眼中显示内皮受损但无前房穿孔。所有标本在切口部位下方的Descemet膜均出现后褶。根据角膜切口方向，视轴周围可能会产生潜在的光学像差。基于这项研究，进行多达8个深切口的放射状角膜切开术可能会产生视觉缺陷。我们建议进行动物研究以评估该手术对角膜尤其是内皮的长期影响。
