Stoichiometry of oxygen consumption in the biosynthesis of isopenicillin from a tripeptide.
作者信息
White R L, John E M, Baldwin J E, Abraham E P
出版信息
Biochem J. 1982 Jun 1;203(3):791-3. doi: 10.1042/bj2030791.
Abstract
The biosynthesis of isopenicillin N from delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine in a cell-free system has been correlated wih O2 consumption by two methods, involving the use of an oxygen-electrode and an n.m.r. spectrometer respectively. The results are consistent with a 1 : 1 stoichiometric ratio for the dioxygen consumed to the isopenicillin N formed.
摘要
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本文引用的文献
1
Cell-free conversion of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine into an antibiotic with the properties of isopenicillin N in Cephalosporium acremonium.
Biochem J. 1979 Nov 15;184(2):427-30. doi: 10.1042/bj1840427.
2
Incorporation of 3H from delta-(L-alpha-amino (4,5-3H)adipyl)-L-cysteinyl-D-(4,4-3H)valine into isopenicillin N.
Biochem J. 1979 Nov 15;184(2):421-6. doi: 10.1042/bj1840421.
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