Coid J, Strang J
Br J Psychiatry. 1982 Jul;141:81-4. doi: 10.1192/bjp.141.1.81.
A case of procyclidine abuse is described in which the clinical presentation was indistinguishable from mania. The patient was a long-standing poly-drug abuser and was obtaining the drugs from medical sources. Controlled exposure on the ward to drugs of abuse, including a double-blind comparison with placebo, confirmed that procyclidine caused a manic response in this patient.