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在强制运动活动诱导的θ波期间,对大鼠海马结构中[14C]2-脱氧葡萄糖摄取的放射自显影分析。

Radioautographic analysis of [14C]2-deoxyglucose uptake in hippocampal formation of the rat during enforced locomotor activity-induced theta.

作者信息

Monmaur P, Orsini J C, Delacour J

出版信息

Brain Res. 1982 Jul 8;243(1):190-6. doi: 10.1016/0006-8993(82)91138-6.

DOI:10.1016/0006-8993(82)91138-6
PMID:7116155
Abstract

The [14C]2-deoxyglucose ( [14C]2-DG) uptake in the hippocampal formation of the rat was studied following enforced locomotor activity-induced theta (M theta). M theta was found to be essentially associated with an increase in 2-DG uptake in the stratum oriens of the hippocampal CA1-CA2 areas. These data contrast with our previous findings that physostigmine-induced theta (I theta) is specifically associated with a decrease in 2-DG uptake in the stratum lacunosum moleculare of hippocampal CA1-CA2 areas. When both of our sets of radioautographic data are considered together, M theta and I theta appear to have a distinct neurophysiological basis.

摘要

在强迫运动诱导的θ波(Mθ)后,研究了大鼠海马结构中[14C]2-脱氧葡萄糖([14C]2-DG)的摄取情况。发现Mθ基本上与海马CA1-CA2区的原层中2-DG摄取增加有关。这些数据与我们之前的发现形成对比,即毒扁豆碱诱导的θ波(Iθ)与海马CA1-CA2区分子层中2-DG摄取减少特异性相关。当将我们两组放射自显影数据一起考虑时,Mθ和Iθ似乎具有不同的神经生理基础。

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