Courtney J M, Park G B, Prentice C R, Winchester J F, Forbes C D
J Bioeng. 1978 Jun;2(3-4):241-9.
Two procedures have been examined for altering the blood compatibility of copolymers of dimethylaminoethyl methacrylate, where blood compatibility has been measured by the recalcification time of platelet rich plasma. The improvement in blood compatibility of a copolymer of dimethylaminoethyl methacrylate and methyl methacrylate resulting from contact with heparin has been shown to be dependent on both copolymer composition and the method of polymerization. The hydrophilicity of a copolymer of dimethylaminoethyl methacrylate and acrylonitrile has been altered by reaction with ethylene oxide gas. The relationship between time of exposure to ethylene oxide gas. The relationship between time of exposure to ethylene oxide gas and clotting time indicates a dependence of compatibility on copolymer hydrophilicity.
已经研究了两种用于改变甲基丙烯酸二甲氨基乙酯共聚物血液相容性的方法，其中血液相容性是通过富含血小板血浆的复钙时间来测定的。甲基丙烯酸二甲氨基乙酯与甲基丙烯酸甲酯的共聚物与肝素接触后血液相容性的改善已表明取决于共聚物组成和聚合方法。甲基丙烯酸二甲氨基乙酯与丙烯腈的共聚物的亲水性已通过与环氧乙烷气体反应而改变。环氧乙烷气体暴露时间之间的关系。环氧乙烷气体暴露时间与凝血时间之间的关系表明相容性取决于共聚物亲水性。
