Chopra S K, Tawashi R
J Pharm Sci. 1982 Aug;71(8):907-11. doi: 10.1002/jps.2600710817.
The tackiness of various tablet coating solutions was determined using a parallel plate technique with a tensile testing machine in conjunction with an oscilloscope where the separation force was displayed as a function of time. Measurements were made at various rates of separation on liquid films of constant thickness. Results showed that the force required to split a liquid film increases with an increase in rate of separation, and that tackiness increases with an increase in viscosity. The relation between tack and viscosity was not linear, and a modified Stefan equation was proposed.
使用平行板技术结合拉伸试验机和示波器来测定各种片剂包衣溶液的粘性,其中分离力作为时间的函数显示出来。在恒定厚度的液膜上以不同的分离速率进行测量。结果表明,分裂液膜所需的力随着分离速率的增加而增加,并且粘性随着粘度的增加而增加。粘性与粘度之间的关系不是线性的,并提出了一个修正的斯特凡方程。