Mäki M, Grönroos P, Vesikari T
J Infect Dis. 1978 Nov;138(5):677-80. doi: 10.1093/infdis/138.5.677.
The invasiveness of Yersinia enterocolitica isolated from the feces of children with diarrhea was assayed in cultured human epithelial (HEp-2) cells. Twenty-one of 24 strains were invasive under the test conditions. Infection with Y. enterocolitica was characterized clinically by exudative diarrhea in 11 cases. Polymorphonuclear leukocytes were demonstrated in the feces from all three cases of exudative diarrhea studied. The results suggest a correlation between enteroinvasiveness of Y. enterocolitica, presence of leukocytes in feces, and clinical exudative diarrhea.
从腹泻儿童粪便中分离出的小肠结肠炎耶尔森菌的侵袭力，在培养的人上皮（HEp-2）细胞中进行了测定。在测试条件下，24株菌株中有21株具有侵袭性。小肠结肠炎耶尔森菌感染的临床特征为11例出现渗出性腹泻。在所研究的3例渗出性腹泻病例的粪便中均发现了多形核白细胞。结果表明小肠结肠炎耶尔森菌的肠侵袭性、粪便中白细胞的存在与临床渗出性腹泻之间存在关联。
