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通过离心增强小肠结肠炎耶尔森菌和大肠杆菌在人喉表皮样癌细胞（HEp-2细胞）中的侵袭性。

Enhancement of invasiveness of Yersinia enterocolitica and Escherichia coli in HEp-2 cells by centrifugation.

作者信息

Vesikari T, Bromirska J, Mäki M

出版信息

Infect Immun. 1982 May;36(2):834-6. doi: 10.1128/iai.36.2.834-836.1982.

DOI:10.1128/iai.36.2.834-836.1982
PMID:7044978
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC351304/
Abstract

Centrifugation enhanced the infectivity of invasive Escherichia coli and Yersinia enterocolitica for HEp-2 cells. Noninvasive bacteria were not endocytosed after centrifugation. The centrifugation procedure may increase the sensitivity of testing for bacterial invasiveness in cell culture without causing false-positive results.

摘要

离心处理增强了侵袭性大肠杆菌和小肠结肠炎耶尔森菌对人喉表皮样癌细胞（HEp-2细胞）的感染性。离心处理后，非侵袭性细菌不会被内吞。离心操作可能会提高细胞培养中细菌侵袭性检测的灵敏度，且不会产生假阳性结果。

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EPITHELIAL CELL PENETRATION AS AN ESSENTIAL STEP IN THE PATHOGENESIS OF BACILLARY DYSENTERY.上皮细胞穿透是细菌性痢疾发病机制中的关键步骤。
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