Sinatra F R, Shah P, Weissman J Y, Thomas D W, Merritt R J, Tong M J
Pediatrics. 1982 Oct;70(4):557-9.
Three infants born to mothers who were hepatitis B surface antigen (HBsAg) positive and had antibody to hepatitis Be antigen (anti-HBe), developed acute icteric hepatitis B within three months of birth. All three infants clinically recovered and developed circulating anti-HBs. Contrary to previous studies, these three cases indicate that mother-infant transmission of the hepatitis B virus (HBV) does occur in infants born to HBsAg-positive, HBe-Ag-negative carrier mothers, and these infants may develop severe acute icteric hepatitis. Therefore, immunoprophylaxis in such newborns may be indicated.
三名母亲为乙型肝炎表面抗原（HBsAg）阳性且有乙型肝炎e抗原抗体（抗-HBe）的婴儿，在出生后三个月内发生了急性黄疸型乙型肝炎。所有三名婴儿临床康复并产生了循环抗-HBs。与先前的研究相反，这三例病例表明，乙型肝炎病毒（HBV）母婴传播确实发生在HBsAg阳性、HBeAg阴性携带者母亲所生的婴儿中，且这些婴儿可能会发展为严重的急性黄疸型肝炎。因此，对此类新生儿可能需要进行免疫预防。
