[乙型肝炎病毒的母婴传播。对21名母亲为乙肝表面抗原阳性的婴儿及6名母亲为乙肝表面抗原阴性但有抗乙肝病毒抗体的婴儿进行随访研究]
[Maternal-fetal transmission of hepatitis B virus. Follow-up study of 21 infants born to HBSAG-positive mothers, and 6 born to HBSAG-negative mothers with anti-HBV antibodies].
作者信息
Manzillo G, Sagnelli E, Da Villa G, Maio G, Izzo C M, Felaco F, Filippini P, Buonocore S, Piccinino F
出版信息
Minerva Med. 1980 Oct 31;71(42):3067-71.
PMID:7266910
Abstract
Vertical transmission of hepatitis B virus (HBV) was studied in 21 mother-infant pairs. A transient HBs-antigenemia was observed in 60% of the 10 children born to HBsAg healthy carrier mothers and 91% of the 11 babies born to mothers with HBsAg-positive CAH. Among the 16 children showing HBs-antigenemia, 3 developed acute viral hepatitis two of whom showed progression to chronicity.
摘要
对21对母婴进行了乙型肝炎病毒（HBV）垂直传播的研究。在10名母亲为HBsAg健康携带者的儿童中，60%出现了短暂的HBs抗原血症；在11名母亲患有HBsAg阳性慢性活动性肝炎（CAH）的婴儿中，91%出现了短暂的HBs抗原血症。在16名出现HBs抗原血症的儿童中，有3名发展为急性病毒性肝炎，其中2名发展为慢性肝炎。
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