精神分裂症患者的眼球运动和眨眼障碍
Disturbances of ocular movements and blinking in schizophrenia.
作者信息
Stevens J R
出版信息
J Neurol Neurosurg Psychiatry. 1978 Nov;41(11):1024-30. doi: 10.1136/jnnp.41.11.1024.
Abstract
Neurological examination and electroencephalograms and electro-oculograms, recorded by telemetry, from unmedicated patients with acute and chronic schizophrenia demonstrate a number of abnormalities of extraocular movement including staring, abnormal blink rate, absent glabellar reflex, and increase in horizontal eye movements. As potential clues to the pathophysiology of schizophrenia, these disturbances are analysed in relation to anatomical substrate and dopamine modulation of ocular movement, rapid eye movement sleep, and the neurological disorders in which similar disturbances of ocular movement occur.
摘要
对未经药物治疗的急慢性精神分裂症患者进行遥测记录的神经学检查、脑电图和眼电图显示，眼球运动存在一些异常，包括凝视、异常眨眼率、眉间反射消失以及水平眼动增加。作为精神分裂症病理生理学的潜在线索，这些障碍将根据眼球运动、快速眼动睡眠的解剖学基础和多巴胺调节以及出现类似眼球运动障碍的神经疾病进行分析。
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