[(Studies on intragastric titration in man) ].

The method of intragastric titration uses food particles for stimulation of gastric acid secretion and is characterised by an excellent reproducibility. The food stimulated gastric acid secretion is influenced by the pH-value of the stimulus, whereas concentration of the peptone solution and volume of the test meal is less important. Postprandial gastrin release, however is altered by pH of the stimulus concentration and volume of the test meal. Intragastric titration represents an excellent method for measuring gastric acid secretion and should mainly be applied to clinical pathophysiological studies.