Siegismund K, Beutner M, Fiedler C
Zentralbl Gynakol. 1982;104(10):615-22.
Postoperative analgesia was achieved by peridural injection of small doses of piritramide (Dipidolor Gedeon Richter Budapest) to 24 gynaecological and surgical patients. Periods of action were longer than those obtainable from equivalent intramuscular or intravenous injections. Undesirable side effects of the opiates, such as disorders of respiration, vomiting, clouded consciousness, and suppression of cough reflex, were not observed. The method did not affect locomotor and sympathetic nerve fibres and, consequently, proved to be superior to postoperative analgesia by means of local anaesthesia. Repetitive injections can be made by nurses. Peridural opiate analgesia can be recommended for postoperative situations and for other patients with pain.
对24例妇科和外科手术患者通过硬膜外注射小剂量匹利卡明(Dipidolor,吉德昂·里奇特公司,布达佩斯)实现术后镇痛。其作用时间比同等剂量肌肉注射或静脉注射的作用时间更长。未观察到阿片类药物的不良副作用,如呼吸紊乱、呕吐、意识模糊和咳嗽反射抑制。该方法不影响运动和交感神经纤维,因此,被证明优于局部麻醉术后镇痛。护士可进行重复注射。硬膜外阿片类镇痛可推荐用于术后情况及其他疼痛患者。