Dawber T R, Nickerson R J, Brand F N, Pool J
Am J Clin Nutr. 1982 Oct;36(4):617-25. doi: 10.1093/ajcn/36.4.617.
The Framingham Study has investigated the effect of host and environmental factors on the development of coronary heart disease since 1949. Serum cholesterol level was determined to the one of the risk factors for coronary heart disease. The nutrient intake, in a subsample of the study population, was determined in 1957. A review of this material has permitted an estimate of egg consumption on each of 912 subjects. The serum cholesterol distribution curves of the subjects according to tertile of egg intake were almost identical, and no relationship between egg intake and coronary heart disease incidence was found. It is concluded that within the range of egg intake of this population differences in egg consumption were unrelated to blood cholesterol level or to coronary heart disease incidence.
自1949年以来,弗明汉姆研究一直在调查宿主和环境因素对冠心病发展的影响。血清胆固醇水平被确定为冠心病的危险因素之一。1957年,对该研究人群的一个子样本进行了营养摄入量测定。对这些数据的审查使得能够估算出912名受试者每人的鸡蛋摄入量。根据鸡蛋摄入量三分位数划分的受试者血清胆固醇分布曲线几乎相同,并且未发现鸡蛋摄入量与冠心病发病率之间存在关联。得出的结论是,在该人群的鸡蛋摄入量范围内,鸡蛋消费量的差异与血液胆固醇水平或冠心病发病率无关。