Greenberg M I, Mayeda D V, Chrzanowski R, Brumwell D, Baskin S I, Roberts J R
Ann Emerg Med. 1982 Oct;11(10):546-8. doi: 10.1016/s0196-0644(82)80428-9.
Atropine sulfate was successfully administered endotracheally to a 74-year-old patient suffering profound bradycardic cardiovascular collapse. Ninety seconds following endotracheal atropine administration, normal blood pressure and pulse were established. Therapeutic blood levels of atropine were documented following endotracheal administration. The endotracheal route for atropine administration appears to provide an effective alternative route of administration when intravenous access is difficult or impossible to establish rapidly.
硫酸阿托品经气管内成功给药于一名74岁患有严重心动过缓性心血管虚脱的患者。气管内给予阿托品90秒后,血压和脉搏恢复正常。气管内给药后记录到了治疗性的阿托品血药浓度。当难以迅速建立静脉通路或无法建立静脉通路时,气管内给予阿托品似乎提供了一种有效的替代给药途径。