Laurie D A, Palmer R W, Hultén M A
Ann Hum Genet. 1982 Jul;46(3):233-44. doi: 10.1111/j.1469-1809.1982.tb00715.x.
An investigation of chiasms distribution in chromosomes 1, 2 and 9 in the human male has shown that each arm consistently has a characteristic and highly non-random distribution of recombination. The chiasma frequencies of chromosome regions corresponding to the major mitotic bands have been used to construct genetic maps under the assumption that there is no chromatid interference or chiasma movement and no difference between meiotic and mitotic band positions. This paper presents genetic lengths and recombination fractions for these bands and for combinations of bands in chromosomes 2 and 9. Our results are particularly useful for relating genetic distance to recombination fraction and for dealing with long stretches of chromosome which cannot easily be analysed by any other techniques.
一项针对人类男性1号、2号和9号染色体交叉分布的调查显示,每条染色体臂都始终具有特征性且高度非随机的重组分布。在不存在染色单体干涉或交叉移动,且减数分裂带位置与有丝分裂带位置无差异的假设下,已使用与主要有丝分裂带相对应的染色体区域的交叉频率来构建遗传图谱。本文给出了这些带以及2号和9号染色体中带的组合的遗传长度和重组率。我们的结果对于将遗传距离与重组率相关联以及处理难以用任何其他技术轻易分析的长染色体片段特别有用。