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[胃肠道恶性淋巴瘤(组织发生、形态发生及组织学诊断问题)]

[Malignant lymphomas of the gastrointestinal tract (problems of histogenesis, morphogenesis and histological diagnosis)].

作者信息

Gordeladze A S, Bystrova V V

出版信息

Arkh Patol. 1982;44(6):14-20.

PMID:7125927
Abstract

Seventy malignant lymphomas of the gastro-intestinal tract (GIT) (54 lymphosarcomas, 16 lymphogranulomatoses) were studied. GIT lymphosarcomas and lymphogranulomatosis are characterized by the similarity of histogenesis, morphogenesis, and forms of progression. The lymphoid apparatus of GIT is the source of tumor growth, the tumor develops multicentrically and not simultaneously, the progression occurs as autochthonous growth, metastasizing. Isolated GIT lymphomas have a potential trend for generalization. In lymphosarcomas, the predominant histological types are prolymphocytic and lymphoblastic, in lymphogranulomatosis--mixed-cell and lymphocyte exhaustion. Differential diagnosis must distinguish between malignant lymphoma and pseudolymphoma, different variants of lymphomas and low-differentiated carcinoma, which requires examination of the operation material, knowledge of the typical cytological and histological features of lymphoma variants, and the use of the required complex of histological and histochemical methods.

摘要

对70例胃肠道恶性淋巴瘤(GIT)(54例淋巴肉瘤,16例淋巴肉芽肿病)进行了研究。胃肠道淋巴肉瘤和淋巴肉芽肿病的特点是组织发生、形态发生和进展形式相似。胃肠道淋巴组织是肿瘤生长的来源,肿瘤多中心发生且不同时出现,进展表现为原位生长并转移。孤立性胃肠道淋巴瘤有泛化的潜在趋势。在淋巴肉瘤中,主要的组织学类型是原淋巴细胞性和淋巴母细胞性,在淋巴肉芽肿病中是混合细胞性和淋巴细胞耗竭性。鉴别诊断必须区分恶性淋巴瘤和假性淋巴瘤、淋巴瘤的不同变体以及低分化癌,这需要检查手术材料,了解淋巴瘤变体的典型细胞学和组织学特征,并使用所需的组织学和组织化学方法组合。

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