Karkinen-Jääskeläinen M, Määttä K, Pasila M, Saxén L
Br J Dis Chest. 1982 Jul;76(3):290-7. doi: 10.1016/0007-0971(82)90056-0.
A fatal case of pulmonary berylliosis in a 59-year-old male is described. Three months after a heavy exposure to the dust of broken fluorescent light bulbs he developed severe respiratory distress with bilateral lower zone opacities on the chest radiograph. Histological examination of a lung biopsy revealed inflammatory changes with a granulomatous component and some necrosis. The diagnosis of berylliosis was confirmed by determination of beryllium in lung tissue by chemical analysis. Two years after the onset of symptoms the patient died of respiratory failure.
本文描述了一例59岁男性的致命性肺铍病病例。在大量接触破碎荧光灯泡粉尘三个月后,他出现了严重的呼吸窘迫,胸部X光片显示双侧下肺野有阴影。肺活检的组织学检查显示有炎症改变,伴有肉芽肿成分和一些坏死。通过化学分析测定肺组织中的铍,证实了铍病的诊断。症状出现两年后,患者死于呼吸衰竭。