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母羊分娩前后母体和胎儿内分泌事件与子宫压力变化的相关性。

Correlations of maternal and fetal endocrine events with uterine pressure changes around parturition in the ewe.

作者信息

Rawlings N C, Ward W R

出版信息

J Reprod Fertil. 1978 Sep;54(1):1-8. doi: 10.1530/jrf.0.0540001.

DOI:10.1530/jrf.0.0540001
PMID:712696
Abstract

In 4 Clun Forest ewes maternal peripheral plasma concentrations of progesterone were still elevated at the onset of parturient uterine activity. Fetal and maternal plasma concentrations of oestrogen started to rise before parturition and concentrations in maternal plasma were positively correlated with parturient uterine activity (P less than 0.05; r = +0.42). Fetal plasma concentrations of corticosteroids were positively correlated with fetal plasma concentrations of oestrogen (P less than 0.01; r = +0.65), but negatively correlated with maternal peripheral plasma progesterone concentrations (P less than 0.05; r = -0.50). Before parturition plasma concentrations of PGF rose but stayed high only in maternal peripheral plasma. Maternal peripheral plasma concentrations of PGF were positively correlated with uterine activity (P less than 0.05; r = +0.79) and plasma concentrations of oestrogen (P less than 0.05; r = +0.79), but negatively correlated with plasma concentrations of progesterone (P less than 0.01; r = -0.54).

摘要

在4只克伦森林母羊中,分娩时子宫活动开始时,母体外周血浆中孕酮浓度仍处于升高状态。分娩前,胎儿和母体血浆中的雌激素浓度开始上升,且母体血浆中的浓度与分娩时子宫活动呈正相关(P<0.05;r=+0.42)。胎儿血浆中的皮质类固醇浓度与胎儿血浆中的雌激素浓度呈正相关(P<0.01;r=+0.65),但与母体外周血浆孕酮浓度呈负相关(P<0.05;r=-0.50)。分娩前,PGF的血浆浓度升高,但仅在母体外周血浆中保持较高水平。母体外周血浆中PGF的浓度与子宫活动呈正相关(P<0.05;r=+0.79),与雌激素血浆浓度呈正相关(P<0.05;r=+0.79),但与孕酮血浆浓度呈负相关(P<0.01;r=-0.54)。

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