McLean A M, Farthing M J, Kurian G, Mathan V I
Br J Radiol. 1982 Oct;55(658):725-8. doi: 10.1259/0007-1285-55-658-725.
Hypoalbuminaemia has been implicated as a possible cause of the radiological abnormalities of the small intestine in tropical sprue. Barium follow-through examination was performed in 35 southern Indian patients with documented tropical sprue, and jejunal width and fold pattern abnormalities were compared with those of a local age-matched control group. Although hypoalbuminaemia was present in 66% of patients with tropical sprue, in only one case was an increase in jejunal calibre associated with a serum albumin concentration below 27 g/l, the threshold below which jejunal dilatation occurs in hypoalbuminaemia alone. These findings suggest that other factors, such as the extent of the mucosal injury, are likely to be more important than hypoalbuminaemia in producing jejunal dilatation in this condition. Abnormalities of fold pattern occurred more frequently than increase in jejunal calibre and appear to be a more sensitive indicator of disease.
低蛋白血症被认为可能是热带口炎性腹泻患者小肠放射学异常的一个原因。对35名有记录的热带口炎性腹泻的印度南部患者进行了钡剂通过检查，并将空肠宽度和皱襞模式异常与当地年龄匹配的对照组进行了比较。虽然66%的热带口炎性腹泻患者存在低蛋白血症，但只有1例空肠管径增加与血清白蛋白浓度低于27g/L有关，这是仅在低蛋白血症时发生空肠扩张的阈值。这些发现表明，在这种情况下，其他因素，如粘膜损伤的程度，可能比低蛋白血症在导致空肠扩张方面更重要。皱襞模式异常比空肠管径增加更频繁出现，似乎是疾病更敏感的指标。
