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推定的1/29罗伯逊易位杂合公牛的减数分裂和精子发生

Meiosis and spermatogenesis in bulls heterozygous for a presumptive 1/29 Robertsonian translocation.

作者信息

Logue D N, Harvey M J

出版信息

J Reprod Fertil. 1978 Sep;54(1):159-65. doi: 10.1530/jrf.0.0540159.

DOI:10.1530/jrf.0.0540159
PMID:712704
Abstract

Bulls heterozygous for the 1/29 Robertsonian translocation showed normal mating behaviour, semen quality and spermatogenesis. The karyotypes of 90 offspring of one heterozygous bull were consistent with a normal 1:1 segregation of the translocation. There was no difference in overall chiasma frequency at diakinesis between heterozygous and normal bulls, and while a trivalent was noted at diakinesis the chiasma position within the No. 1 arm of the trivalent did not appear to be altered when compared with that found in the normal No. 1 bivalent. An increased frequency of aneuploid secondary spermatocytes at the second meiotic division (M II) was found in the heterozygous bulls, the rate of non-disjuction based on the proportion of hypermodal cells being raised from 2.8% in the normal to 6.4% in the heterozygous animals.

摘要

携带1/29罗伯逊易位的杂合子公牛表现出正常的交配行为、精液质量和精子发生。一头杂合子公牛的90个后代的核型与该易位正常的1:1分离一致。杂合子公牛和正常公牛在终变期的总交叉频率没有差异,虽然在终变期观察到一个三价体,但与正常1号二价体相比,三价体1号臂内的交叉位置似乎没有改变。在杂合子公牛中,发现第二次减数分裂(M II)时非整倍体次级精母细胞的频率增加,基于超模式细胞比例的不分离率从正常动物的2.8%提高到杂合子动物的6.4%。

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