梅毒血清和免疫复合物对自然杀伤细胞活性的抑制作用。
Depression of natural killer cell activity by syphilitic serum and immune complexes.
作者信息
Jensen J R, Jørgensen A S, Thestrup-Pedersen K
出版信息
Br J Vener Dis. 1982 Oct;58(5):298-301. doi: 10.1136/sti.58.5.298.
Abstract
Consecutive serum samples were obtained from patients with syphilis before and on three occasions after treatment. The sera contained immunosuppresive factors associated with the immunoglobulin fraction, which could depress the natural killer cell activity of healthy controls. There was no evidence that allogeneic or lymphocytotoxic antibodies played a role in immuno-suppression, which could be reproduced with both soluble and insoluble antigen-IgG-antibody complexes.
摘要
从梅毒患者治疗前及治疗后三个不同时间点采集连续的血清样本。这些血清中含有与免疫球蛋白部分相关的免疫抑制因子，该因子可抑制健康对照者的自然杀伤细胞活性。没有证据表明同种异体抗体或淋巴细胞毒性抗体在免疫抑制中起作用，可溶性和不溶性抗原 - IgG - 抗体复合物均可导致免疫抑制。
相似文献
1
Depression of natural killer cell activity by syphilitic serum and immune complexes.梅毒血清和免疫复合物对自然杀伤细胞活性的抑制作用。
Br J Vener Dis. 1982 Oct;58(5):298-301. doi: 10.1136/sti.58.5.298.
2
Fluctuations in natural killer cell activity in early syphilis.早期梅毒患者自然杀伤细胞活性的波动
Br J Vener Dis. 1983 Feb;59(1):30-2. doi: 10.1136/sti.59.1.30.
3
Natural cytotoxicity in systemic lupus erythematosus: mechanisms of suppression by inhibitory serum factors.系统性红斑狼疮中的自然细胞毒性：抑制性血清因子的抑制机制。
Clin Exp Immunol. 1983 Aug;53(2):363-70.
4
Natural cell mediated cytotoxicity in systemic lupus erythematosus: suppression by antilymphocyte antibody.系统性红斑狼疮中的自然细胞介导细胞毒性：抗淋巴细胞抗体的抑制作用
Arthritis Rheum. 1980 Nov;23(11):1274-81. doi: 10.1002/art.1780231108.
5
Inhibition of normal natural killer cytotoxicity by sera from hemophilic patients.
Immunol Lett. 1993 May;36(2):153-9. doi: 10.1016/0165-2478(93)90047-6.
6
[Circulating immune complexes and NK activity in systemic lupus erythematosus].
Immun Infekt. 1984 Apr;12(2):109-10.
7
Circulating immune complexes in experimental syphilis and their relation to immunological response against Treponema pallidum.实验性梅毒中的循环免疫复合物及其与抗梅毒螺旋体免疫反应的关系。
FEMS Microbiol Immunol. 1991 Apr;3(2):83-91. doi: 10.1111/j.1574-6968.1991.tb04201.x.
8
Simian immunodeficiency virus (SIV)/immunoglobulin G immune complexes in SIV-infected macaques block detection of CD16 but not cytolytic activity of natural killer cells.感染猴免疫缺陷病毒（SIV）的猕猴体内的SIV/免疫球蛋白G免疫复合物可阻断CD16的检测，但不影响自然杀伤细胞的细胞溶解活性。
Clin Vaccine Immunol. 2006 Jul;13(7):768-78. doi: 10.1128/CVI.00042-06.
9
K-cell activity in aplastic anaemia.
Scand J Haematol. 1983 May;30(5):451-7. doi: 10.1111/j.1600-0609.1983.tb02533.x.
10
[Functional characteristics and clinical importance of the K cells (a review of the literature)].[K细胞的功能特性及临床重要性（文献综述）]
Vrach Delo. 1982 Nov(11):17-21.
引用本文的文献
1
Fluctuations in natural killer cell activity in early syphilis.早期梅毒患者自然杀伤细胞活性的波动
Br J Vener Dis. 1983 Feb;59(1):30-2. doi: 10.1136/sti.59.1.30.
2
3
Immune studies in infants with congenital syphilis.先天性梅毒婴儿的免疫研究。
Clin Exp Immunol. 1990 Aug;81(2):315-8. doi: 10.1111/j.1365-2249.1990.tb03337.x.
本文引用的文献
1
Autolymphocytotoxins in syphilis.梅毒中的自身淋巴细胞毒素
Br J Vener Dis. 1980 Oct;56(5):297-301. doi: 10.1136/sti.56.5.297.
2
Natural killer cell activity in syphilis.梅毒中的自然杀伤细胞活性。
Arch Dermatol Res. 1982;272(1-2):163-5. doi: 10.1007/BF00510409.
3
Alterations in T lymphocytes and T-lymphocyte subpopulations in patients with syphilis.梅毒患者T淋巴细胞及T淋巴细胞亚群的改变。
Br J Vener Dis. 1982 Feb;58(1):18-22. doi: 10.1136/sti.58.1.18.
4
Leucocyte migration and cell-mediated immunity in syphilis.梅毒中的白细胞迁移与细胞介导免疫
Br J Vener Dis. 1972 Dec;48(6):483-8. doi: 10.1136/sti.48.6.483.
5
Reduced lymphocyte transformation due to a plasma factor in patients with active syphilis.活动性梅毒患者血浆因子导致淋巴细胞转化降低。
Lancet. 1969 Aug 2;2(7614):246-7. doi: 10.1016/s0140-6736(69)90010-5.
6
Selective phagocytic paralysis induced by immobilized immune complexes.固定化免疫复合物诱导的选择性吞噬麻痹
J Exp Med. 1975 Oct 1;142(4):827-38. doi: 10.1084/jem.142.4.827.
7
Inhibition of lymphocyte mitogenesis by immobilized antigen-antibody complexes.固定化抗原-抗体复合物对淋巴细胞有丝分裂的抑制作用。
J Exp Med. 1975 Oct 1;142(4):814-26. doi: 10.1084/jem.142.4.814.
8
Surface markers on human b and t lymphocytes. VI. Cytotoxicity against cell lines as a functional marker for lymphocyte subpopulations.人类B淋巴细胞和T淋巴细胞的表面标志物。VI. 对细胞系的细胞毒性作为淋巴细胞亚群的功能标志物。
Int J Cancer. 1975 Apr 15;15(4):596-605. doi: 10.1002/ijc.2910150409.
9
Reactivity of lymphocytes from patients with syphilis towards T. pallidum antigen in the leucocyte migration and lymphocyte transformation tests.梅毒患者淋巴细胞在白细胞迁移试验和淋巴细胞转化试验中对梅毒螺旋体抗原的反应性。
Br J Vener Dis. 1976 Aug;52(4):224-9. doi: 10.1136/sti.52.4.224.
Zotero 插件