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豚鼠和兔心房中喹吖因阳性神经元的荧光组织化学定位。

Fluorescent histochemical localisation of quinacrine-positive neurones in the guinea-pig and rabbit atrium.

作者信息

Crowe R, Burnstock G

出版信息

Cardiovasc Res. 1982 Jul;16(7):384-90. doi: 10.1093/cvr/16.7.384.

DOI:10.1093/cvr/16.7.384
PMID:7127352
Abstract

Quinacrine-fluorescent nerve fibres and nerve cell bodies are described in the right and left atria of the guinea-pig and rabbit. The nerve cells (20 to 35 micrometers in diameter) are found predominantly in the right atrium in both species. The nerve fibres are varicose and innervate both the muscle and many blood vessels. The quinacrine fluorescent neural structures are unaffected by chemical sympathectomy with 6-hydroxydopamine. The distribution of quinacrine-positive nerve fibres and cell bodies are compared to the distribution of adrenergic and acetylcholinesterase-positive nerves in the atrium of both species. Quinacrine fluorescence appears to be selective for non-adrenergic, non-cholinergic nerves and the possibility that it is binding to high contents of ATP discussed.

摘要

在豚鼠和兔子的左右心房中描述了喹吖因荧光神经纤维和神经细胞体。神经细胞(直径20至35微米)在这两个物种的右心房中占主导地位。神经纤维有曲张,支配肌肉和许多血管。喹吖因荧光神经结构不受6-羟基多巴胺化学交感神经切除术的影响。将喹吖因阳性神经纤维和细胞体的分布与这两个物种心房中肾上腺素能和乙酰胆碱酯酶阳性神经的分布进行了比较。喹吖因荧光似乎对非肾上腺素能、非胆碱能神经具有选择性,并讨论了其与高含量ATP结合的可能性。

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Fluorescent histochemical localisation of quinacrine-positive neurones in the guinea-pig and rabbit atrium.豚鼠和兔心房中喹吖因阳性神经元的荧光组织化学定位。
Cardiovasc Res. 1982 Jul;16(7):384-90. doi: 10.1093/cvr/16.7.384.
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