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牛接种ERA狂犬病疫苗后的抗体水平。

Antibody levels following ERA rabies vaccine in cattle.

作者信息

Di Trani L, Irsara A, Ciuchini F, Pestalozza S, Orfei Z

出版信息

Comp Immunol Microbiol Infect Dis. 1982;5(1-3):199-203. doi: 10.1016/0147-9571(82)90038-8.

DOI:10.1016/0147-9571(82)90038-8
PMID:7128071
Abstract

The humoral response in cattle treated with ERA strain rabies vaccine, was studied utilizing the following criteria: antibody titres determined by RFFIT, seroimmunological monitoring of experimentally vaccinated animals, a comparison of data obtained from cattle vaccinated and maintained under field conditions in the absence of anamnestic information. The average antibody responses in the field experiment are in agreement with the laboratory animal response, both showing highest levels at day 15 after vaccination; at day 30 in both groups the immune response is sensibly lower, to remain then on a constant level after day 90 and stay about 0.5 I.U./ml up to the fifteenth month.

摘要

利用以下标准研究了用ERA株狂犬病疫苗治疗的牛的体液反应:通过快速荧光灶抑制试验(RFFIT)测定抗体滴度,对实验接种动物进行血清免疫学监测,比较在无既往史信息的情况下在野外条件下接种并饲养的牛的数据。野外实验中的平均抗体反应与实验动物的反应一致,两者在接种后第15天均显示出最高水平;两组在第30天时免疫反应明显较低,然后在第90天后保持在恒定水平,直至第15个月一直维持在约0.5国际单位/毫升。

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