Korvenranta H J, Kero P O, Välimäki I A
Eur J Pediatr. 1982 Jul;138(4):297-300. doi: 10.1007/BF00442500.
The intraesophageal pressure difference (delta Pes) was measured in 46 preterm infants, 36 with respiratory distress (RDS). It was 12.7 +/- 2.9 mm Hg (mean +/- SEM) in severe RDS, 9.6 +/- 3.2 mm Hg in moderate RDS, and 5.2 +/- 1.6 mm Hg in infants with mild disease, measured at the age of 8 h. These intergroup differences were highly significant (P less than 0.001). During the first 96 h of life the delta Pes decreased to 6.1 +/- 1.1 mm Hg in severe RDS and to 4.8 +/- 1.2 mm Hg in moderate RDS. These changes were also highly significant (P less than 0.001) when compared with respective initial values. In infants with mild disease and in healthy preterm infants, the delta Pes did not alter significantly during the first 96 h of life. The correlations between gastric aspirate L/S ratio and the delta Pes at the age of 8 h (r = -0.65, P less than 0.001) and at the age of 24 h (r = -0.73, P less than 0.001) were highly significant. It is concluded that intraesophageal pressure monitoring is a valuable tool in the intensive care evaluation of the severity of RDS.
对46例早产儿进行了食管内压差（ΔPes）测量，其中36例患有呼吸窘迫综合征（RDS）。在出生8小时时测量，重度RDS患儿的ΔPes为12.7±2.9 mmHg（均值±标准误），中度RDS患儿为9.6±3.2 mmHg，轻症患儿为5.2±1.6 mmHg。这些组间差异具有高度显著性（P＜0.001）。在出生后的前96小时内，重度RDS患儿的ΔPes降至6.1±1.1 mmHg，中度RDS患儿降至4.8±1.2 mmHg。与各自的初始值相比，这些变化也具有高度显著性（P＜0.001）。在轻症患儿和健康早产儿中，出生后前96小时内ΔPes无明显变化。出生8小时（r = -0.65，P＜0.001）和24小时（r = -0.73，P＜0.001）时胃吸出物L/S比值与ΔPes之间的相关性具有高度显著性。结论是，食管内压力监测是RDS严重程度重症监护评估中的一项有价值的工具。
