Thomson A, Elliott J, Silverman M
Arch Dis Child. 1983 Nov;58(11):891-6. doi: 10.1136/adc.58.11.891.
Measurements of dynamic lung compliance (Cdyn) were made on 42 occasions in a group of 15 intubated very low birthweight infants with respiratory distress syndrome, using an oesophageal balloon and pneumotachograph system. Values of Cdyn were compared with those of total respiratory system compliance (Crs) using an occlusion technique. Ten very low birthweight infants with no respiratory disease were similarly studied while breathing through a facemask. The occlusion tests for oesophageal balloon assessment were unsatisfactory in 14 of 15 intubated infants, but in only 3 of the 10 normal infants. Values of Cdyn were poorly reproducible and correlated poorly with Crs. We conclude that in sick intubated preterm infants oesophageal pressure (and hence Cdyn) cannot be reliably measured, but that Crs may be a useful parameter of lung stiffness.
在一组15名患有呼吸窘迫综合征的极低出生体重插管婴儿中,使用食管气囊和呼吸流速仪系统对动态肺顺应性(Cdyn)进行了42次测量。使用阻断技术将Cdyn值与全呼吸系统顺应性(Crs)值进行比较。对10名无呼吸系统疾病的极低出生体重婴儿通过面罩呼吸时进行了类似研究。在15名插管婴儿中,有14名婴儿的食管气囊评估阻断试验结果不理想,但在10名正常婴儿中只有3名结果不理想。Cdyn值的重复性差,与Crs的相关性也差。我们得出结论,在患病的插管早产儿中,食管压力(以及由此得出的Cdyn)无法可靠测量,但Crs可能是肺硬度的一个有用参数。