Philips J B, Beale E F, Howard J E, Jaeger M J, Eitzman D V
Biol Neonate. 1980;38(5-6):270-5. doi: 10.1159/000241376.
A simplified method of determining dynamic respiratory compliance (C dyn) in the newborn is described. Studies were performed during mechanical ventilation on 24 infants with respiratory distress syndrome (RDS) and 6 infants without RDS. Cdyn was evaluated at pressure settinghs of 20/0, 25/5 and 30/10 cm H2O. Significant decreases (p < 0.05) in Cdyn were noted with each increase in end-expiratory pressure setting. The values for Cdyn in RDS patients obtained by this method closely approximated previously published data for lung compliance in babies with RDS. This simple and reproducible method may be useful in following the course of illness in infants with RDS.
本文描述了一种用于测定新生儿动态呼吸顺应性（Cdyn）的简化方法。对24例患有呼吸窘迫综合征（RDS）的婴儿和6例无RDS的婴儿在机械通气期间进行了研究。在呼气末压力设置为20/0、25/5和30/10 cm H₂O时评估Cdyn。随着呼气末压力设置的每次增加，Cdyn均出现显著下降（p < 0.05）。通过这种方法获得的RDS患者的Cdyn值与先前发表的RDS婴儿肺顺应性数据非常接近。这种简单且可重复的方法可能有助于追踪RDS婴儿的病程。
