Keighley M R, Eastwood D, Ambrose N S, Allan R N, Burdon D W
Gastroenterology. 1982 Dec;83(6):1271-5.
The incidence of abdominal and pelvic abscess is reported from a consecutive series of 111 patients undergoing 124 resections for Crohn's disease. Preoperative abscesses were found as a complication of Crohn's disease in 13 patients (10%) and 8 were clinically unsuspected. The majority of preoperative abscesses were confined to one site (localized to bowel, psoas sheath, pelvis, or in the abdominal wall). All preoperative abscesses occurred in patients requiring an emergency or urgent operation. Patients with a preoperative abscess had significantly lower serum albumin levels and significantly increased serum alkaline phosphatase values than the patients without an abscess. Postoperative abscesses occurred in 17 patients (14%) and six were multiple. Five of the postoperative abscesses occurred in patients who had had a preoperative abscess; these recurrent abscesses all presented 6-14 wk after an uncomplicated initial operation. The principal bacterial isolates were Escherichia coli (54%), Bacteroides fragilis (44%), enterococci (41%), and viridans streptococci (31%). The incidence of abscess was unrelated to the use of preoperative steroid therapy.
对111例因克罗恩病接受124次切除术的患者进行连续观察，报告了腹部和盆腔脓肿的发生率。术前脓肿作为克罗恩病的并发症在13例患者（10%）中被发现，其中8例临床未被怀疑。大多数术前脓肿局限于一个部位（局限于肠道、腰大肌鞘、盆腔或腹壁）。所有术前脓肿均发生在需要急诊或紧急手术的患者中。与没有脓肿的患者相比，有术前脓肿的患者血清白蛋白水平显著降低，血清碱性磷酸酶值显著升高。术后脓肿发生在17例患者（14%）中，6例为多发。5例术后脓肿发生在术前有脓肿的患者中；这些复发性脓肿均在初次手术无并发症后6 - 14周出现。主要分离出的细菌为大肠埃希菌（54%）、脆弱拟杆菌（44%）、肠球菌（41%）和草绿色链球菌（31%）。脓肿的发生率与术前使用类固醇治疗无关。
