Lombardo J M, Lanks K W
In Vitro. 1982 Mar;18(3 Pt 1):251-3. doi: 10.1007/BF02618578.
Cell lines derived from a murine neuroblastoma, Clone N18, were cured of their M. hyorhinis infection by in vivo passage. The major variable determining success of this method was found to be the incubation time in vivo. Infected cells maintained in vivo for 27 d or more and then placed in culture were free of mycoplasma whereas those maintained in vivo for 7 or 14 d were found to still be infected. This approach to eliminating mycoplasma infection may be successful using other tumor cell lines.
源自小鼠神经母细胞瘤克隆N18的细胞系通过体内传代治愈了猪鼻支原体感染。发现决定该方法成功的主要变量是体内孵育时间。在体内维持27天或更长时间然后置于培养中的受感染细胞没有支原体，而在体内维持7天或14天的细胞仍被发现受到感染。使用其他肿瘤细胞系，这种消除支原体感染的方法可能会成功。
