Michalak T, Nowosławski A
Intervirology. 1982;17(4):247-52. doi: 10.1159/000149295.
Large crystalline accumulations of hepatitis B core antigen (HBcAg) particles were detected in the cytoplasm of hepatocytes from a patient with mild reactive hepatitis. Within these crystals, the core particles showed a symmetrical hexagonal arrangement with the center-to-center particle distance estimated at 24 nm. The possible mechanism of aggregation and the significance of HBcAg crystalline lattice in the preservation of hepatitis B virus are discussed.
在一名轻度反应性肝炎患者的肝细胞胞质中检测到大量乙型肝炎核心抗原（HBcAg）颗粒的结晶聚集体。在这些晶体中，核心颗粒呈对称的六边形排列，颗粒中心间距估计为24纳米。本文讨论了聚集的可能机制以及HBcAg晶格在乙肝病毒保存中的意义。
