Ito E T, Cihlar R L, Inderlied C B
J Bacteriol. 1982 Nov;152(2):880-7. doi: 10.1128/jb.152.2.880-887.1982.
Lipid synthesis increases coordinately with protein and RNA synthesis during morphogenesis of Mucor racemosus. The lipid synthesis inhibitor cerulenin can completely block morphogenesis under conditions in which cell growth continues. An increase in phospholipid turnover may be an important correlate to morphogenesis of Mucor spp., especially the turnover of phosphotidyl inositol and phosphatidyl ethanolamine. The increase in ornithine decarboxylase, which occurs during morphogenesis, is inhibited by the addition of cerulenin.
在总状毛霉形态发生过程中,脂质合成与蛋白质和RNA合成协同增加。脂质合成抑制剂浅蓝菌素在细胞生长持续的条件下可完全阻断形态发生。磷脂周转率的增加可能是毛霉属形态发生的一个重要关联因素,尤其是磷脂酰肌醇和磷脂酰乙醇胺的周转率。形态发生过程中出现的鸟氨酸脱羧酶增加,会因添加浅蓝菌素而受到抑制。