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正常宿主中汉逊德巴利酵母引起的骨感染:一例报告

Bone infection caused by debaryomyces hansenii in a normal host: a case report.

作者信息

Wong B, Kiehn T E, Edwards F, Bernard E M, Marcove R C, de Harven E, Armstrong D

出版信息

J Clin Microbiol. 1982 Sep;16(3):545-8. doi: 10.1128/jcm.16.3.545-548.1982.

DOI:10.1128/jcm.16.3.545-548.1982
PMID:7130364
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC272406/
Abstract

Debaryomyces hansenii was isolated from a cystic lesion in the distal tibia of a healthy 23-year-old woman. Ascospores were demonstrated when the organism was incubated at 25 but not at 30 degrees C. Electron microscopy was necessary to demonstrate the warty surface of the ascospore wall. Growth was inhibited in vitro by low concentrations of amphotericin B, 5-fluorocytosine, miconazole, and ketoconazole. Four previous cases of infection caused by Debaryomyces spp. and one caused by the related fungus Torulopsis candida were reviewed.

摘要

汉逊德巴利酵母从一名23岁健康女性胫骨远端的囊性病变中分离得到。该菌在25℃培养时可形成子囊孢子,而在30℃培养时则不能。需通过电子显微镜观察才能显示子囊孢子壁的疣状表面。低浓度的两性霉素B、5-氟胞嘧啶、咪康唑和酮康唑在体外可抑制其生长。回顾了之前4例由德巴利酵母属引起的感染病例以及1例由相关真菌假丝酵母引起的感染病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3233/272406/2dd5c73a62ba/jcm00146-0163-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3233/272406/27695c1f6b51/jcm00146-0161-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3233/272406/af003a73e9cd/jcm00146-0162-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3233/272406/6618617a8809/jcm00146-0162-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3233/272406/2dd5c73a62ba/jcm00146-0163-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3233/272406/27695c1f6b51/jcm00146-0161-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3233/272406/af003a73e9cd/jcm00146-0162-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3233/272406/6618617a8809/jcm00146-0162-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3233/272406/2dd5c73a62ba/jcm00146-0163-a.jpg

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Electron microscopy of ascus formation in the yeast debaryomyces hansenii.
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