Angulo Miriam, Reyes-Becerril Martha, Medina-Córdova Noe, Tovar-Ramírez Dariel, Angulo Carlos
Immunology & Vaccinology Group, Centro de Investigaciones Biológicas del Noroeste, SC, Instituto Politécnico Nacional 195, Playa Palo de Santa Rita Sur, La Paz, B.C.S., C.P. 23096, Mexico.
Instituto Nacional de Investigaciones Forestales, Agrícolas y Pecuarias, Campo Experimental Todos Santos, Agricultura s/n entre México y Durango, Emiliano Zapata, La Paz, B.C.S., C.P: 23070, Mexico.
Appl Microbiol Biotechnol. 2020 Sep;104(18):7689-7699. doi: 10.1007/s00253-020-10780-z. Epub 2020 Jul 20.
Debaryomyces hansenii comes of age as a new potential probiotic for terrestrial and aquatic animals. Probiotic properties, including inmunostimulatory effects, gut microbiota modulation, enhanced cell proliferation and differentiation, and digestive function improvements have been related to the oral delivery of D. hansenii. Its functional compounds, such as cell wall components and polyamines, have been identified and implicated in its immunomodulatory activity. In addition, in vitro studies using immune cells have shown standpoints on the possible recognition, regulation, and effector immune mechanisms stimulated by this yeast. This review describes historic, cutting-edge research findings, implications, and perspectives on the use of D. hansenii as a promising probiotic for animals. KEY POINTS: • Debaryomyces hansenii has probiotic effects in terrestrial and aquatic animals. • Nutritional effects could be associated to probiotic D. hansenii strains. • β-D-Glucan and polyamines from D. hansenii are associated to probiotic properties. • Adoption by the industry is expected in the next years.
汉逊德巴利酵母成为陆地和水生动物新型潜在益生菌。益生菌特性，包括免疫刺激作用、肠道微生物群调节、增强细胞增殖和分化以及改善消化功能，都与口服汉逊德巴利酵母有关。其功能化合物，如细胞壁成分和多胺，已被鉴定并涉及其免疫调节活性。此外，使用免疫细胞的体外研究揭示了这种酵母可能引发的识别、调节和效应免疫机制的观点。本综述描述了关于将汉逊德巴利酵母用作动物有前景的益生菌的历史、前沿研究成果、影响和展望。要点：• 汉逊德巴利酵母对陆地和水生动物有益生菌作用。• 营养作用可能与益生菌汉逊德巴利酵母菌株有关。• 汉逊德巴利酵母的β-D-葡聚糖和多胺与益生菌特性有关。• 预计未来几年该行业会采用。
