模糊性与遗传密码的进化

Ambiguity and the evolution of the genetic code.

作者信息

Kocherlakota R R, Acland N D

出版信息

Orig Life. 1982 Mar;12(1):71-80. doi: 10.1007/BF00926913.

Abstract

The evolution of the genetic code is an extremely complex problem. The addition of a new method by which the code could evolve, however, allows much to be explained about the way in which the present codes (gamma 3 and gamma 3) originated. The idea that ambiguity would allow the length of the codon to change is very useful, since it predicts the distribution of the 4-blocs and 2-blocs in the code, determines where variations in the code are probable, and presents a scenario for the evolution of the code.

摘要

遗传密码的进化是一个极其复杂的问题。然而，一种新的密码进化方式的出现，使得我们能够对当前密码（γ3和γ3）的起源方式做出诸多解释。密码模糊性会使密码子长度发生变化这一观点非常有用，因为它预测了密码中4联体和2联体的分布，确定了密码可能发生变化的位置，并为密码的进化提供了一种设想。