三种软体动物5S核糖体RNA的序列证实了动态二级结构模型的有效性。
Sequences of three molluscan 5 S ribosomal RNAs confirm the validity of a dynamic secondary structure model.
作者信息
Fang B L, De Baere R, Vandenberghe A, De Wachter R
出版信息
Nucleic Acids Res. 1982 Aug 11;10(15):4679-85. doi: 10.1093/nar/10.15.4679.
Abstract
The collection of known 5 S rRNA primary structures is enriched with the sequences from three mollusca, the snails Helix pomatia and Arion rufus, and the mussel Mytilus edulis. The three sequences can be fitted in a five-helix secondary structure model previously shown (De Wachter et al. (1982) Biochimie 64, 311-329) to apply to all 5 S RNAs regardless of their origin. One of the helices in this model can undergo a bulge-internal loop transition. Within the metazoan kingdom, the dimensions of each helix and loop are rigidly conserved, except for one helix which can comprise either 6 or 7 base pairs.
摘要
已知的5S rRNA一级结构集合中富含来自三种软体动物的序列，即蜗牛玛瑙螺和红蛞蝓，以及贻贝紫贻贝。这三个序列可以拟合到先前显示的（德瓦赫特等人，（1982年）《生物化学》64卷，311 - 329页）适用于所有5S RNA（无论其来源如何）的五螺旋二级结构模型中。该模型中的一个螺旋可以经历凸起 - 内环转变。在后生动物界中，每个螺旋和环的尺寸严格保守，除了一个螺旋可以包含6或7个碱基对。
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