Chee T P, Prakash N S, Desser K B, Benchimol A
Am Heart J. 1982 Nov;104(5 Pt 1):974-7. doi: 10.1016/0002-8703(82)90428-8.
A prospective study of 182 patients undergoing cardiac surgery was performed. The patients were divided into three groups. Group I consisted of 83 patients who had never been treated with digitalis. Group II comprised 59 patients who were taking digoxin before operation and had medication discontinued 24 to 48 hours prior to surgery; they did not receive maintenance digoxin in the postoperative periods. Group III was made up of 40 patients who were given prophylactic digoxin in the perioperative period; none had taken digoxin before. Sixty of 83 group I patients (72%) and two of the group III patients (5%) developed postoperative supraventricular tachyarrhythmia. Digoxin was reinstituted in 56 of group II patients (95%) for supraventricular arrhythmia and/or heart failure. Of the various factors evaluated, only valvular surgery and ECG evidence of myocardial infarction were associated with postoperative supraventricular tachyarrhythmias.
对182例接受心脏手术的患者进行了一项前瞻性研究。患者被分为三组。第一组由83例从未接受过洋地黄治疗的患者组成。第二组包括59例术前服用地高辛且在手术前24至48小时停药的患者；他们在术后未接受维持剂量的地高辛。第三组由40例在围手术期给予预防性地高辛的患者组成；他们之前均未服用过地高辛。第一组83例患者中有60例（72%）以及第三组2例患者（5%）发生了术后室上性快速心律失常。第二组56例患者（95%）因室上性心律失常和/或心力衰竭重新使用了地高辛。在评估的各种因素中，只有瓣膜手术和心肌梗死的心电图证据与术后室上性快速心律失常有关。
