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[1975 - 1979年德意志民主共和国首都柏林的乳腺恶性肿瘤]

[Malignant neoplasms of the breast in the capital of the German Democratic Republic, Berlin, 1975-1979].

作者信息

Ebeling K, Tanneberger S, Nischan P, Jarofke D, Kluge E

出版信息

Arch Geschwulstforsch. 1982;52(4):307-21.

PMID:7138243
Abstract

Some important data characterizing the situation in breast cancer control were analyzed in the capital of the German Democratic Republic, Berlin, during the period from 1975 to 1979. In comparison with former periods a progress is demonstrated by a decrease of the diagnostic interval, an increase of stages I and II (73%), an increase of patients treated with radical surgery (85.1%) and an improvement of the relative 5-year-survival rate (67.8% of all stages and age groups). The relative 5-year-survival rate is significantly higher in patients treated in a comprehensive cancer centre with strictly multidisciplinary treatment (75.8%) than in those treated in all other hospitals (63.5%). For patients treated in hospitals with less than 20 new cases per year the survival rate is significantly lower (59.4%), especially for the advanced stages III and IV. Further progress in breast cancer control can be expected by improvement of early detection, centralization of treatment in hospitals with specialized oncological team work and a well organized follow-up system.

摘要

1975年至1979年期间,在德意志民主共和国首都柏林对一些表征乳腺癌防治情况的重要数据进行了分析。与之前时期相比,诊断间隔缩短、Ⅰ期和Ⅱ期病例增加(73%)、接受根治性手术治疗的患者增加(85.1%)以及相对5年生存率提高(所有分期和年龄组为67.8%),这些都表明取得了进展。在采用严格多学科治疗的综合癌症中心接受治疗的患者,其相对5年生存率(75.8%)显著高于在所有其他医院接受治疗的患者(63.5%)。对于每年新病例少于20例的医院所治疗的患者,生存率显著较低(59.4%),尤其是Ⅲ期和Ⅳ期晚期患者。通过改进早期检测、在配备专业肿瘤治疗团队的医院集中治疗以及建立组织完善的随访系统,有望在乳腺癌防治方面取得进一步进展。

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