三价铬的皮肤吸收：组织水平及换血治疗

Cutaneous absorption of trivalent chromium: tissue levels and treatment by exchange transfusion.

作者信息

Kelly W F, Ackrill P, Day J P, O'Hara M, Tye C T, Burton I, Orton C, Harris M

出版信息

Br J Ind Med. 1982 Nov;39(4):397-400. doi: 10.1136/oem.39.4.397.

DOI:10.1136/oem.39.4.397

PMID:7138799

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1009073/

Abstract

ABSTRACT A man was accidentally immersed in hot acidic trivalent chromium sulphate solution but none was swallowed. The clinical course was dominated by burns, intravascular haemolysis, and acute renal failure. Blood concentrations of chromium were measured during treatment and tissue concentrations were measured at death. Exchange transfusion reduced blood chromium concentrations by two-thirds. The total quantities of chromium absorbed and removed by various routes were calculated. In-vitro studies showed that the chromium solution did not directly cause haemolysis.

摘要

摘要一名男子意外浸入热的酸性硫酸三价铬溶液中，但未吞咽任何溶液。临床过程以烧伤、血管内溶血和急性肾衰竭为主。治疗期间测定了血液中的铬浓度，死亡时测定了组织中的铬浓度。换血使血液铬浓度降低了三分之二。计算了通过各种途径吸收和清除的铬总量。体外研究表明，铬溶液不会直接导致溶血。