晒黑致死——一例致命的碱式硫酸铬中毒病例。

Death by tanning--a case of fatal basic chromium sulphate poisoning.

作者信息

van Heerden P V, Jenkins I R, Woods W P, Rossi E, Cameron P D

机构信息

Department of Intensive Care, Sir Charles Gairdner Hospital, Nedlands, Western Australia.

出版信息

Intensive Care Med. 1994;20(2):145-7. doi: 10.1007/BF01707671.

DOI:10.1007/BF01707671

PMID:8201096

Abstract

A woman ingested 400 ml of leather tanning solution containing 48 g of basic chromium sulphate (CrOHSO4). This substance forms hydrogen ions and trivalent chromium when it reacts with tissue proteins. The patient died of cardiogenic shock, complicated by pancreatitis and gut mucosal necrosis and haemorrhage. There are no reported cases of toxicity due to oral ingestion of trivalent chromium. Toxicity of hexavalent and trivalent chromium is discussed and suggestions made for management of future cases.

摘要

一名女性摄入了400毫升含有48克碱式硫酸铬（CrOHSO4）的皮革鞣制溶液。该物质与组织蛋白反应时会形成氢离子和三价铬。患者死于心源性休克，并发胰腺炎、肠道黏膜坏死和出血。尚无口服三价铬中毒的报道病例。本文讨论了六价铬和三价铬的毒性，并对未来病例的处理提出了建议。