Owen R A, Melton L J, Ilstrup D M, Johnson K A, Riggs B L
Clin Orthop Relat Res. 1982 Nov-Dec(171):37-43.
The prevention of hip fractures, a major cause of morbidity and mortality in the elderly, is hampered by insufficient knowledge of the population at risk. A Colles' fracture associated with minor trauma is indicative of an overall 50% increase in the risk of a subsequent hip fracture. The relative risk of a subsequent hip fracture is greater for men with Colles' fracture (RR = 6.4) than for women (RR = 1.3). Among women, the risk is increased more than twofold for those whose Colles' fractures occurred at the age of 70 or older but is not increased for younger women. That greater predictive power was not achieved may be due to differences in the pathophysiology of osteoporosis at various fracture sites.
髋部骨折是老年人发病和死亡的主要原因，对高危人群认识不足阻碍了对其的预防。与轻微创伤相关的Colles骨折表明随后发生髋部骨折的风险总体增加50%。Colles骨折男性发生后续髋部骨折的相对风险（RR = 6.4）高于女性（RR = 1.3）。在女性中，70岁及以上发生Colles骨折的女性风险增加两倍以上，而年轻女性则未增加。未能实现更大的预测能力可能是由于不同骨折部位骨质疏松症的病理生理学存在差异。
