Mária V, József M
Morphol Igazsagugyi Orv Sz. 1978 Oct;18(4):257-63.
In the Department of the Pathology of the University of Pécs in 1953--1977 autopsy of 58 cases of myeloma multiplex (MM) and plasmacytoma (P) was performed and among them 4 cases of sarcoma was found. In the material of the Cytologic Center of the Academical Commission of Pécs two more cases of sarcoma occurred. According to the authors findings in the MM-autopsy material (I) in addition to the frequent "plasmocytic-plasmoblastic MM" in a few number (II) immunoblastic tumours could also be seen (immunoblastic MM). "Immunoblastic MM" disseminates more frequently (lymph nodes, spleen, kidney, liver) and the patients die earlier than in cases of "plasmocytic-plasmoblastic MM". Since sarcomatous changes appear to be polymorph and disseminated, for the reliable diagnosis examination of tissue specimens taken from several parts of the tumour is necessary. Recent data and the authors studies show, that immunoglobulin-producing tumours differ each other according to the degree of maturity of plasma cells
1953年至1977年期间，佩奇大学病理学系对58例多发性骨髓瘤（MM）和浆细胞瘤（P）进行了尸检，其中发现4例肉瘤。在佩奇学术委员会细胞学中心的材料中又出现了2例肉瘤。根据作者在MM尸检材料中的发现：（I）除了常见的“浆细胞 - 浆母细胞性MM”外，少数情况下（II）还可见免疫母细胞性肿瘤（免疫母细胞性MM）。“免疫母细胞性MM”比“浆细胞 - 浆母细胞性MM”更易发生播散（淋巴结、脾脏、肾脏、肝脏），且患者死亡更早。由于肉瘤样改变似乎具有多形性且呈播散性，因此为了进行可靠诊断，有必要对取自肿瘤多个部位的组织标本进行检查。最新数据和作者的研究表明，产生免疫球蛋白的肿瘤根据浆细胞的成熟程度而有所不同
