Suppr超能文献

J. 博尔德研究所(1969 - 1975年)可手术乳腺癌的远距离钴治疗经验。

Experience of telecobalt therapy in operable breast cancer at J. Bordet Institute (1969-1975).

作者信息

Regnier R, Nguyen T H, Balikdjian D, Lustman-Maréchal J, Smets P, Darquennes H, Henry J

出版信息

Int J Radiat Oncol Biol Phys. 1982 Sep;8(9):1517-23. doi: 10.1016/0360-3016(82)90611-3.

Abstract

Between 1969 and 1975, postoperative radiotherapy was performed at the J. Bordet Institute on 787 stage I-III operable breast cancer patients. Crude 10 years survival rates are respectively 61% for stage I, 59% for stage II and 30% for stage III. The results have been analysed according to clinical characteristics of significant prognostic value and according to the technical conditions of treatment. The status of the axillary nodes appears to be the most important prognostic factor. Radiotherapy to the thoracic wall and lymph drainage areas has varied little throughout the whole period with the dose to the internal mammary chain being the only parameter which varied significantly. Loco-regional recurrences occurred only in 5, 2% of patients without distant metastases appearing previously or during the following year (2.4 for stage I patients). Severe sequelae were seen in only a very few cases. Survival appears significantly correlated with an adequate dose of irradiation to mammary node chain.

摘要

1969年至1975年间,J. 博尔德研究所对787例I - III期可手术乳腺癌患者进行了术后放疗。I期、II期和III期患者的10年粗生存率分别为61%、59%和30%。根据具有显著预后价值的临床特征以及治疗的技术条件对结果进行了分析。腋窝淋巴结状态似乎是最重要的预后因素。在整个期间,胸壁和淋巴引流区的放疗变化不大,唯一有显著变化的参数是内乳链的剂量。局部区域复发仅发生在5.2%的患者中,这些患者在之前或随后一年没有出现远处转移(I期患者为2.4%)。仅在极少数病例中出现了严重后遗症。生存率似乎与对乳腺淋巴结链的足够照射剂量显著相关。

相似文献

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验