Ahmed A R, Schreiber P, Abramovits W, Ostreicher M, Lowe N J
J Am Acad Dermatol. 1982 Oct;7(4):478-83. doi: 10.1016/s0190-9622(82)70129-x.
Three cases of the simultaneous occurrence of lichen planus (LP) and systemic lupus erythematosus (SLE) are presented. Each patient had clinical, histologic, and immunopathologic LP. Additionally, each patient had clinical SLE that fulfilled the American Rheumatism Association criteria for the diagnosis of SLE. The clinical manifestations of SLE were predominantly cutaneous. The three patients had positive lupus band test and high titers of antinuclear antibodies. One patient had vitiligo in addition to SLE and LP. LP and SLE have common clinical, histologic, and immunopathologic features. It is possible that a common agent (or agents) may cause either disease or the overlap syndrome, depending on the immunogenetic predisposition of the patient.
本文报告了3例扁平苔藓（LP）与系统性红斑狼疮（SLE）同时发生的病例。每位患者均有临床、组织学及免疫病理学表现的LP。此外，每位患者均有符合美国风湿病学会SLE诊断标准的临床SLE。SLE的临床表现主要为皮肤症状。3例患者狼疮带试验均为阳性，且抗核抗体滴度高。1例患者除SLE和LP外还患有白癜风。LP和SLE具有共同的临床、组织学及免疫病理学特征。根据患者的免疫遗传易感性，可能是一种共同因素（或多种因素）导致了这两种疾病或重叠综合征。
