一个西西里家庭中的遗传性二十甲营养不良症。

Pavone L, Li Volti S, Guarneri B, La Rosa M, Sorge G, Incorpora G, Mollica F

J Med Genet. 1982 Oct;19(5):337-40. doi: 10.1136/jmg.19.5.337.

Over three successive generations four members of a Sicilian family showed early onset, slowly progressive dystrophy of the finger and toe nails, without any other anomalies or skin signs. Histological examination performed in two patients enabled us to discount lichen planus and other underlying diseases. The hereditary and idiopathic nature of the disease is underlined and a classification of the dystrophies affecting all the 20 nails is proposed.

在一个西西里家庭的连续三代人中，有四名成员表现出指甲和趾甲的早发性、缓慢进行性营养不良，无任何其他异常或皮肤体征。对两名患者进行的组织学检查使我们能够排除扁平苔藓和其他潜在疾病。强调了该疾病的遗传性和特发性，并提出了一种影响所有20个指甲的营养不良分类。