Bale E, White F H
J Microsc. 1982 Oct;128(Pt 1):69-78. doi: 10.1111/j.1365-2818.1982.tb00438.x.
The present study was designed to clarify the morphological nature of epithelial-connective tissue attachment by quantitative comparison of palatal and buccal mucosae. Tissue samples were obtained from ferrets and, following a strict sampling regime, sections were obtained for quantitative light and electron microscopy. Electron micrographs from the epithelial-connective tissue junction were subjected to analysis by serological intersection counting. Quantitative results show that palatal epithelium has a comparatively convoluted interface, and is twice as thick as buccal epithelium. Stereological data are presented for relative surface area of basal plasma membrane occupied by hemidesmosomes, mean hemidesmosomal diameter and numerical density of hemidesmosomes per unit area of basal plasma membrane. Larger hemidesmosomes are found in the palatal epithelium. Results suggest that a prominent rete-ridge pattern, as seen in the palatal epithelium, along with a greater specialized surface for adhesion, may be responsible for providing epithelial-connective tissue stability in regions subjected to high mechanical stress.
本研究旨在通过对上腭黏膜和颊黏膜进行定量比较，阐明上皮-结缔组织附着的形态学本质。从雪貂身上获取组织样本，并遵循严格的采样方案，获取用于定量光镜和电镜检查的切片。对上皮-结缔组织交界处的电子显微照片进行血清学交叉计数分析。定量结果表明，腭上皮具有相对曲折的界面，厚度是颊上皮的两倍。给出了关于半桥粒占据的基底质膜相对表面积、平均半桥粒直径以及每单位基底质膜面积半桥粒的数值密度的体视学数据。在上腭上皮中发现了更大的半桥粒。结果表明，腭上皮中所见的明显的嵴状突模式，以及更大的专门粘附表面，可能是在承受高机械应力的区域提供上皮-结缔组织稳定性的原因。
