Haywood L J, Sharma O P, Siegel M E, Siegel R J, Gottlieb S L, Caldwell J, Siemsen J K
J Natl Med Assoc. 1982 Oct;74(10):959-64.
Thallium 201 myocardial perfusion scanning revealed focal left ventricular defects at rest in four of 30 patients (13 percent) with systemic sarcoidosis. All the defects decreased in size during thallium stress imaging, a finding opposite of that usually seen in myocardial ischemia. Nine patients had abnormal right ventricular visualization at rest. Thus, 11 of 30 (37 percent) had abnormal resting myocardial scand. Two of the four patients with left ventricular defects were studied serially for up to 1.5 years to evaluate response to corticosteroid therapy. The myocardial defect diminished in one patient, whereas the second patient, maintained for 2 years on low doses of steroids, had no resolution. In patients suspected of focal myocardial involvement by sarcoidosis on thallium scanning dynamic changes in scan defects can occur during exercise which are the reverse of those usually seen in coronary artery disease. These defects probably represent myocardial sarcoid. Right ventricular uptake generally appears to correlate with the severity of pulmonary involvement by sarcoidosis, yet does not appear to be a specific finding.
铊 201 心肌灌注扫描显示，30 例系统性结节病患者中有 4 例（13%）在静息状态下存在左心室局灶性缺损。在铊负荷显像期间，所有缺损的大小均减小，这一发现与心肌缺血时通常所见的情况相反。9 例患者在静息状态下右心室显影异常。因此，30 例中有 11 例（37%）静息心肌扫描异常。对 4 例左心室缺损患者中的 2 例进行了长达 1.5 年的连续研究，以评估对皮质类固醇治疗的反应。1 例患者的心肌缺损缩小，而另 1 例接受低剂量类固醇治疗 2 年的患者，缺损未得到缓解。在铊扫描中怀疑有结节病局灶性心肌受累的患者，运动期间扫描缺损可出现动态变化，这与冠状动脉疾病通常所见的情况相反。这些缺损可能代表心肌结节病。右心室摄取一般似乎与结节病肺部受累的严重程度相关，但似乎不是一个特异性表现。
